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Mastra vs OpenAI Agents SDK

Two agent frameworks tools for AI agents, side by side. Facts come from each tool's own site.

Mastra

mastra.ai

TypeScript framework for agents with memory, tools, MCP, and workflows.

Open sourceNew
Visit Mastra

OpenAI Agents SDK

openai.github.io

OpenAI's lightweight Python framework for multi-agent workflows.

Open sourceNew
Visit OpenAI Agents SDK
Mastra compared with OpenAI Agents SDK
MastraOpenAI Agents SDK
What it doesTypeScript framework for agents with memory, tools, MCP, and workflows.OpenAI's lightweight Python framework for multi-agent workflows.
In their wordsTypeScript AI Framework for Agents and Apps | MastraOpenAI Agents SDK
Open sourceYesYes
Websitemastra.aiopenai.github.io
Link checked2026-10-162026-10-16

More options:Alternatives to MastraAlternatives to OpenAI Agents SDKGuide: Best AI agent frameworks

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